The absence of curative therapies for advanced or recurrent forms of prostate cancer has
prompted a vigorous search for novel treatment strategies. Immunotherapy encompasses
one particularly promising systemic approach to treat prostate cancer. Immune-based
strategies to treat prostate cancer have recently been facilitated by the identification of a
number of prostate tissue/tumor antigens that can be targeted, either by antibody or T cells,
to promote prostate tumor cell injury or death. These same prostate antigens can also be …

Whereas androgen deprivation and chemotherapy have become the cornerstone of therapy
for advanced prostate cancer, novel therapies are being developed that may expand upon
currently available treatments. The identification of antigens expressed by prostate tissue
and/or prostate cancer that are recognized by T cells or antibodies creates opportunities to
develop novel immunotherapeutic approaches including tumor vaccines. Proteins
expressed in prostate cancer including prostate-specific antigen, prostatic acid …

Whereas androgen deprivation and chemotherapy have become the cornerstone of therapy
for advanced prostate cancer, novel therapies are being developed that may expand upon
currently available treatments. The identification of antigens expressed by prostate tissue
and/or prostate cancer that are recognized by T cells or antibodies creates opportunities to
develop novel immunotherapeutic approaches including tumor vaccines. Proteins
expressed in prostate cancer—including prostate-specific antigen, prostatic acid …