[HTML][HTML] The TATA-less Promoter of Mouse Ribonucleotide Reductase R1 Gene Contains a TFII-I Binding Initiator Element Essential for Cell Cycle-regulated …
E Johansson, E Skogman, L Thelander - Journal of Biological Chemistry, 1995 - ASBMB
Mammalian ribonucleotide reductase shows S-phase specific expression and consists of
two non-identical subunits, proteins R1 (large subunit) and R2 (small subunit). A comparison
between the human and mouse TATA-less R1 gene promoters revealed four highly
conserved DNA regions, while the remaining sequence showed a low degree of
conservation. Two regions, α and β, were earlier identified as protein binding regions in the
mouse R1 promoter by using DNase footprinting technique. The two new regions are …
two non-identical subunits, proteins R1 (large subunit) and R2 (small subunit). A comparison
between the human and mouse TATA-less R1 gene promoters revealed four highly
conserved DNA regions, while the remaining sequence showed a low degree of
conservation. Two regions, α and β, were earlier identified as protein binding regions in the
mouse R1 promoter by using DNase footprinting technique. The two new regions are …