Initiation of antihypertensive treatment during nonsteroidal anti-inflammatory drug therapy

JH Gurwitz, J Avorn, RL Bohn, RJ Glynn, M Monane… - Jama, 1994 - jamanetwork.com
Objective.—To determine whether there is an increased risk for the initiation of
antihypertensive therapy in older persons prescribed nonaspirin, nonsteroidal anti-
inflammatory drugs (NSAIDs). Design.—Case-control study. Setting.—New Jersey Medicaid
program. Patients.—Medicaid enrollees aged 65 years and older. The 9411 case patients
were newly started on an antihypertensive medication between November 1981 and
February 1990. A similar number of controls were randomly selected among other enrollees …