[HTML][HTML] Prostaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neurons
MD Southall, MR Vasko - Journal of Biological Chemistry, 2001 - ASBMB
Although a number of prostaglandin E 2 (PGE 2) receptor subtypes have been cloned,
limited studies have been performed to elucidate subtypes that subserve specific actions of
this eicosanoid, in part because of a paucity of selective receptor antagonists. Using reverse
transcription-polymerase chain reaction (PCR) and antisense oligonucleotides, we
examined which prostaglandin E 2 receptor (EP receptor) subtypes are expressed in
sensory neurons and which mediate the PGE 2-induced increase in cAMP production and …
limited studies have been performed to elucidate subtypes that subserve specific actions of
this eicosanoid, in part because of a paucity of selective receptor antagonists. Using reverse
transcription-polymerase chain reaction (PCR) and antisense oligonucleotides, we
examined which prostaglandin E 2 receptor (EP receptor) subtypes are expressed in
sensory neurons and which mediate the PGE 2-induced increase in cAMP production and …