Mechanisms of Ca2+-dependent transcription

B Mellström, JR Naranjo - Current opinion in neurobiology, 2001 - Elsevier
B Mellström, JR Naranjo
Current opinion in neurobiology, 2001Elsevier
Ca2+ has a central role in coupling synaptic activity and transcriptional responses. Recent
studies have focused on Ca2+-dependent nuclear mechanisms that bring to the
nucleosomal level cascades of events initiated in the submembranous space at the
synapse. In addition, a new Ca2+-dependent interaction between a calcium sensor and
DNA has been shown to regulate transcription directly.
Ca2+ has a central role in coupling synaptic activity and transcriptional responses. Recent studies have focused on Ca2+-dependent nuclear mechanisms that bring to the nucleosomal level cascades of events initiated in the submembranous space at the synapse. In addition, a new Ca2+-dependent interaction between a calcium sensor and DNA has been shown to regulate transcription directly.
Elsevier