[HTML][HTML] Functional conservation of platelet glycoprotein V promoter between mouse and human megakaryocytes

N Sato, N Kiyokawa, T Taguchi, T Suzuki… - Experimental …, 2000 - Elsevier
OBJECTIVE: In an attempt to clarify the megakaryo-specific regulatory mechanism of GPV
gene transcription, we characterized the 5′-flanking region of the mouse GPV gene.
MATERIALS AND METHODS: The promotor activity of a− 481/+ 22 5′-fragment of the
mouse GPV gene was examined in normal mouse bone marrow cells (BMC) and various
human cell lines using two distinct reporter gene assay systems, luciferase and green
fluorescence protein (GFP). RESULTS: When a DNA construct consisting of this fragment …