Defining progression in nonmuscle invasive bladder cancer: it is time for a new, standard definition

D Lamm, R Persad, M Brausi, R Buckley, JA Witjes… - The Journal of …, 2014 - Elsevier
Purpose Despite being one of the most important clinical outcomes in nonmuscle invasive
bladder cancer, there is currently no standard definition of disease progression. Major
clinical trials and meta-analyses have used varying definitions or have failed to define this
end point altogether. A standard definition of nonmuscle invasive bladder cancer
progression as determined by reproducible and reliable procedures is needed. We examine
current definitions of nonmuscle invasive bladder cancer progression, and propose a new …