Although the best known actions of vitamin D involve its regulation of bone mineral
homeostasis, vitamin D exerts its influence on many physiologic processes. One of these
processes is the immune system. Both the adaptive and innate immune systems are
impacted by the active metabolite of vitamin D, 1, 25 (OH) 2 D. These observations have
important implications for understanding the predisposition of individuals with vitamin D
deficiency to infectious diseases such as tuberculosis as well as to autoimmune diseases …