[HTML][HTML] Novel mechanism of negative regulation of 1, 25-dihydroxyvitamin D3-induced 25-hydroxyvitamin D3 24-hydroxylase (Cyp24a1) Transcription: epigenetic …
The SWI/SNF chromatin remodeling complex facilitates gene transcription by remodeling
chromatin using the energy of ATP hydrolysis. Recent studies have indicated an interplay
between the SWI/SNF complex and protein-arginine methyltransferases (PRMTs). Little is
known, however, about the role of SWI/SNF and PRMTs in vitamin D receptor (VDR)-
mediated transcription. Using SWI/SNF-defective cells, we demonstrated that Brahma-
related gene 1 (BRG1), an ATPase that is a component of the SWI/SNF complex, plays a …
chromatin using the energy of ATP hydrolysis. Recent studies have indicated an interplay
between the SWI/SNF complex and protein-arginine methyltransferases (PRMTs). Little is
known, however, about the role of SWI/SNF and PRMTs in vitamin D receptor (VDR)-
mediated transcription. Using SWI/SNF-defective cells, we demonstrated that Brahma-
related gene 1 (BRG1), an ATPase that is a component of the SWI/SNF complex, plays a …