REP-2, a Rab escort protein encoded by the choroideremia-like gene.
FP Cremers, SA Armstrong, MC Seabra… - Journal of Biological …, 1994 - ASBMB
Rab escort proteins (REPs) bind to newly synthesized Rab proteins and remain bound
during and after the attachment of a geranylgeranyl (GG) group by the catalytic component
of the Rab GG transferase. Transfer of the GG group is absolutely dependent on the
participation of a REP. REP-1, the first characterized REP, is produced by a gene on the X
chromosome that is defective in patients with choroideremia, a form of retinal degeneration.
Cremers et al.(Cremers, FPM, Molloy, CM, van de Pol, DJR, van den Hurk, JAJM, Bach, I …
during and after the attachment of a geranylgeranyl (GG) group by the catalytic component
of the Rab GG transferase. Transfer of the GG group is absolutely dependent on the
participation of a REP. REP-1, the first characterized REP, is produced by a gene on the X
chromosome that is defective in patients with choroideremia, a form of retinal degeneration.
Cremers et al.(Cremers, FPM, Molloy, CM, van de Pol, DJR, van den Hurk, JAJM, Bach, I …
