Congenital cytomegalovirus infection: outcome and diagnosis

SA Ross, SB Boppana - Seminars in pediatric infectious diseases, 2005 - Elsevier
Cytomegalovirus (CMV) is the most common congenital infection in humans and an
important cause of morbidity and mortality in immunocompromised hosts. Congenital CMV
infection occurs in approximately 0.5 to 1 percent of all newborns in the United States and
can result in significant neurological sequelae. The gold standard for diagnosing congenital
CMV infection is isolation of the virus from infants within the first 2 weeks of life through
conventional or rapid cell culture techniques. Newer molecular diagnostic methods to …